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Seahawks vs. Cardinals TNF — What to Know For Betting
Sep 25th, 2025

Key Storylines & Matchups

  • Push in the NFC West — Both Seattle and Arizona enter with 2–1 records, each hoping to avoid a 0–2 start in division play. (New York Post)

  • Seahawks dominance historically — Seattle currently holds a seven-game winning streak in the series. (CBSSports.com)

  • Injury updates — Seahawks RB Zach Charbonnet is likely to return after missing last game. (Reuters)
    Meanwhile, the Cardinals lose James Conner for the season to a severe ankle injury. (Field Gulls)

  • Seattle’s depth move — The Seahawks have elevated practice‐squad linemen to bolster the trenches ahead of this matchup. (Field Gulls)

Predictions, Odds, & Betting Angles

  • Spread & total — Seattle is a narrow favorite (–1.5), and the over/under is landing around 43.5 points. (CBSSports.com)

  • Expert picks diverge — Some lean Seahawks to win; others see a closer Arizona victory. (CBSSports.com)

  • Player prop angles — A few bettors favor:
     • Jaxon Smith-Njigba to log over 68.5 receiving yards (Sports Handle)
     • Kenneth Walker III to score a touchdown (Sports Handle)
     • Leaning under on total points scored (Sports Handle)


🔗 Preview Links You Should Include

  • NFL’s “Three Must-Know Storylines” for Seahawks vs. Cardinals — A high-level breakdown of what to watch in prime time (NFL.com)

  • CBS Sports — TNF Prediction & Odds — Spread, moneyline, and expert leanings (CBSSports.com)

  • SportsHandle — Picks & Predictions (Moneyline & Under) — Prop bets, AI analysis, and game overview (Sports Handle)

  • Fieldgulls — “Behind Seahawks Enemy Lines” Preview — A Seattle-fan lens previewing challenges in Arizona (Field Gulls)

  • Fieldgulls — “5 Game Predictions vs. Cardinals” — Specific player and game predictions to watch (Field Gulls)

  • Revenge of the Birds — Cardinals’ outlook vs. Seahawks — How Arizona is preparing, roster concerns, and betting odds (Revenge of the Birds)

 

Posted by Elton Maloney (Profile) | Permalink | Comments (0) | Trackbacks (0)
Advisor to Joe Duffy's Picks as far as organic handicapping. An expert on matchups and other statistical analysis and research.
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